Publications

(MBU-Lab members are highlighted in bold)

*Equal contribution

2022

Demmer JK, Phillips BP, Uhrig OL, Filloux A, Allsopp LP, Bublitz M, Meier T. Structure of ATP synthase from ESKAPE pathogen Acinetobacter baumannii.
Sci Adv. 2022 Feb 18;8(7):eabl5966. doi: 10.1126/sciadv.abl5966

2021

Heit S, Geurts MMG, Murphy BJ, Corey RA, Mills DJ, Kühlbrandt W, Bublitz M. Structure of the hexameric fungal plasma membrane proton pump in it sautoinhibited state.
Sci Adv. 2021 Nov 12;7(46):eabj5255. doi: 10.1126/sciadv.abj5255

Simcock PW, Bublitz M, Cipcigan F, Ryadnov MG, Crain J, Stansfeld PJ, Sansom MSP. Membrane Binding of Antimicrobial Peptides Is Modulated by Lipid Charge Modification.
J Chem Theory Comput. 2021 Jan 4. doi: 10.1021/acs.jctc.0c01025. Online ahead of print. PMID: 33395285

2020

Geurts MMG*, Clausen JD*, Arnou B*, Montigny C, Lenoir G, Corey RA, Jaxel C, Møller JV, Nissen P, Andersen JP, le Maire M, Bublitz M.The SERCA residue Glu340 mediates interdomain communication that guides Ca2+ transport.
Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31114-31122. doi: 10.1073/pnas.2014896117. Epub 2020 Nov 23. PMID: 33229570 Free PMC article.

El Omari K, Mohamad N, Bountra K, Duman R, Romano M, Schlegel K, Kwong HS, Mykhaylyk V, Olesen C, Moller JV, Bublitz M, Beis K, Wagner A. Experimental phasing with vanadium and application to nucleotide-binding membrane proteins.
IUCrJ. 2020 Oct 14;7(Pt 6):1092-1101. doi: 10.1107/S2052252520012312. eCollection 2020 Nov 1. PMID: 33209320 Free PMC article.

Hankins MTK, Bublitz M. Observing bacterial membrane proteins in their quasi-natural habitat.
Nat Rev Microbiol. 2020 Sep 30. doi: 10.1038/s41579-020-00463-x. Online ahead of print

Marchesini M, Gherli A, Montanaro A, Patrizi L, Sorrentino C, Pagliaro L, Rompietti C, Kitara S, Heit S, Olesen CE, Møller JV, Savi M, Bocchi L, Vilella R, Rizzi F, Baglione M, Rastelli G, Loiacono C, La Starza R, Mecucci C, Stegmaier K, Aversa F, Stilli D, Lund Winther AM, Sportoletti P, Bublitz M, Dalby-Brown W, Roti G. (2020)Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol doi: 10.1016/j.chembiol.2020.04.002

2018

Bublitz M, Kjellerup L, Cohrt KO, Gordon S, Mortensen AL, Clausen JD, Pallin TD, Hansen JB, Fuglsang AT, Dalby-Brown W, Winther AL. (2018)Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity. PloS one
doi: 10.1371/journal.pone.0188620.

2016

Hahn A, Parey K, Bublitz M, Mills DJ, Zickermann V, Vonck J, Kühlbrandt W, Meier T. (2016) Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology. Mol Cell doi: 10.1016/j.molcel.2016.05.037.

Clausen JD*, Bublitz M*, Arnou B, Olesen C, Andersen JP, Møller JV, Nissen P. (2016) Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. Structure 24(4):617-23.

Karlsen JL, Bublitz M. (2016) How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations: The P-Type ATPase Example. Methods Mol Biol 1377:523-39.

2015

Nass K, Foucar L, Barends TR, Hartmann E, Botha S, Shoeman RL, Doak RB, Alonso-Mori R, Aquila A, Bajt S, Barty A, Bean R, Beyerlein KR, Bublitz M, Drachmann N, Gregersen J, Jönsson HO, Kabsch W, Kassemeyer S, Koglin JE, Krumrey M, Mattle D, Messerschmidt M, Nissen P, Reinhard L, Sitsel O, Sokaras D, Williams GJ, Hau-Riege S, Timneanu N, Caleman C, Chapman HN, Boutet S, Schlichting I. (2015) Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. J Synchrotron Radiat 22(Pt 2):225-38.

Bublitz M, Nass K, Drachmann ND, Markvardsen AJ, Gutmann, MJ, Barends TR, Mattle D, Shoeman RL, Doak RB, Boutet S, Messerschmidt M, Seibert MM, Williams GJ, Foucar L, Reinhard L, Sitsel O, Gregersen JL, Clausen JD, Boesen T, Gotfryd K, Wang KT, Olesen C, Møller JV, Nissen P, Schlichting I. (2015) Structural studies of P-type ATPase ligand complexes using an X-ray free-electron laser. IUCrJ 2(Pt4): 409-20.

2014

Drachmann ND, Olesen C, Møller JV, Guo Z, Nissen P, Bublitz M. (2014) Comparing crystal structures of Ca2+-ATPase in the presence of different lipids. FEBS Journal 281(18): 4249-62.

Penner RC, Andersen ES, Jensen JL, Kantcheva AK, Bublitz M, Nissen P, Rasmussen AM, Svane KL, Hammer B, Rezazadegan R, Nielsen NC, Nielsen JT, Andersen JE. (2014) Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. Nat Commun 5:5803.

Montigny C, Decottignies P, Le Maréchal P, Capy P, Bublitz M, Olesen C, Møller JV, Nissen P, le Maire M. (2014) S-palmitoylation and s-oleoylation of rabbit and pig sarcolipin. J Biol Chem 289(49):33850-61.

More Publications…